Scientist I/II

Scientist I/II

Location: Singapore (Biopolis)

Full Time

Job Description

The candidate will work closely with our senior management and lead scientists in the area of drug target discovery, with focus in oncology and immuno-oncology.  They will plan and execute critical experiments, including in partnership with service companies and pharma partners. The successful candidate will bring cutting-edge, hands-on industry or equivalent academic expertise in immuno-oncology, including use of T cells and other human immune cell populations. The candidate will have demonstrated experience leading cross-functional projects with external collaborators.


  • Hands-on molecular and cell biology in support of genetic screening, experimental design, resource planning, execution, and data analysis.

  • Characterization of new targets and work with bioinformaticians to investigate gene networks involved in immune cell functioning.

  • Design studies to validate novel targets using in vitro CRISPR-Cas screens in mammalian cells.

  • Bring capability of transcriptomics efforts- establishing both bulk and single cell RNA-seq technologies and data analysis platform.

  • Work collaboratively with the Engine teams in Asia and US.

  • Involved in collaborations with external partners, including academic labs.

  • Writing scientific work plans and project proposals and managing budgets, timelines, communications, and priorities.

  • Contribute to scientific strategy and planning as necessary.

The above listed responsibilities are essential duties associated with this position; however, they are not an exhaustive list. Changes to individual responsibilities may occur due to business needs.


  • Ph.D. with 3+ years of relevant work experience in cell biology / molecular biology / genomics. In depth understanding of immune-oncology.

  • Proven track record in planning and execution of genomic screens, e.g. CRISPR-Cas, RNAi, and use of functional genomics data for therapeutic target identification.

  • Strong experimental molecular and cell biology techniques, such as mammalian tissue culture.

  • Preferred experience in developing successful collaborations and relationships with academic and/or industrial partners and KoLs.

  • Excellence and rigor in data interpretation skills, demonstrated by a successful track record in overseeing projects.

  • Cross-functional team experience, including experience working with global teams is a plus.

  • Excellent interpersonal communication skills – verbal, written, and presentations.

  • Experience mentoring junior scientists and research associates.

  • 1-3 years of pharma R&D experience is preferred.

  • Strong peer-reviewed publication record

In addition to above, the candidate will be expected to have:

  • Ability to work in a multi-disciplinary team across time-zones.

  • Ability to prioritize responsibilities and multi-task effectively.

  • Excellent documentation and organization skills.

  • Ability to maintain confidentiality and security of project information.

  • Self-motivated, willing to learn, and able to work independently on projects.

  • Willingness to mentor junior scientists and research associates.

Apply Now

To apply, please e-mail your CV to