Scientist II/Senior Scientist

Scientist II/ Senior Scientist

Location: San Francisco Bay Area (San Carlos, CA)

Full Time

Engine Biosciences is pioneering network biomedicine, combining high-throughput, massively parallel biological experimentation with high-throughput computation to empower better drug development.  Integrating these, we can address targets inaccessible by conventional approaches. We are looking for a medicinal chemist to reduce to practice these computational and experimental efforts by designing and synthesizing drug candidate molecules. As a member of our Engine team, you will join with a group of hard-charging, creative scientists in our approach to drug discovery and to precison medicines.


As a key member of the Chemistry team, you will have significant impact on Engine’s success by:

  • Synthesizing novel, target-focused small molecule compounds
  • Analyzing project data, and working within the Team in the design of compounds to progress them to optimized lead and preclinical candidate stage
  • Being a partner in the scientific success of other scientists in the full Engine Team, and creating an environment where we channel everyone’s scientific curiosity to build our portfolio
  • Developing an appreciation for the functional areas beyond Chemistry, and having input into new technology developments, implementation into new methods and experimental strategies
  • Supporting all Chemistry activities, contributing to internal Engine meetings, and to written reports
  • Contributing to the external face of Engine Biosciences at professional meetings and through publications in peer-reviewed journals
  • Contributing to our intellectual property portfolio

Education, Experience, and Attributes

Education, Experience, and Attributes

  • Ph.D. degree in chemistry with through understanding of organic and synthetic chemistry methods and associated analytical and purification techniques.
  • Postdoctoral experience and a minimum of 2 or more years of industrial experience
  • A strong track record of scientific productivity as exemplified by publications, patents, and meeting abstracts
  • Troubleshooting and problem-solving skills, and the ability to work in a Team and apply these skills to others’ research efforts
  • Excellent written and verbal communication skills
  • Strong sense of organization and precise record-keeping
  • Comfort with a fast-paced environment, and the ability to work with, and contribute to, cross-functional teams.
  • Some experience in computer assisted drug design
  • Experience in oncology medicinal chemistry and systems biology would be a plus

Apply Now

To apply, please e-mail your CV to